Type I interferon‐activated microglia are critical for neuromyelitis optica pathology #DSFN5

Type I interferonâactivated microglia are critical for neuromyelitis optica pathology
Type I interferon is detrimental in experimental NMO. Microglia respond to Type I IFN in experimental NMO. Microglia…
onlinelibrary.wiley.com
Wium-Andersen, M.K., Villumsen, M.D., Wium-Andersen, I.K. et al. The familial and genetic contribution to the association between depression and cardiovascular disease: a twin cohort study. Mol Psychiatry (2020). #DSFN5

The familial and genetic contribution to the association between depression and cardiovascular disease: a twin cohort study
Depression and cardiovascular disease (ischemic heart disease and stroke) are associated in a bidirectional manner. Thei…
doi.org
Aarøe, L., Appadurai, V., Hansen, K.M. et al. Genetic predictors of educational attainment and intelligence test performance predict voter turnout. Nat Hum Behav (2020). #DSFN5

Genetic predictors of educational attainment and intelligence test performance predict voter turnout
The genetic variance that predicts educational attainment or intelligence test performance predicts individual-level voter …
doi.org
Yuste, R., Hawrylycz, M., Aalling, N. et al. A community-based transcriptomics classification and nomenclature of neocortical cell types. Nat Neurosci 23, 1456–1468 (2020). https://doi.org/10.1038/s41593-020-0685-8 #DSFN5
Brain-informed speech separation (BISS) for enhancement of target spea… #DSFN5

Brain-informed speech separation (BISS) for enhancement of target speaker in multitalker speech perception
Hearing-impaired people often struggle to follow the speech stream of an individual talker in noisy environments. Rece…
www.sciencedirect.com
Beneficial effects of cerebellar tDCS on motor learning are associated… #DSFN5

Beneficial effects of cerebellar tDCS on motor learning are associated with altered putamen-cerebellar connectivity: A simultaneous tDCS-fMRI study
Non-invasive transcranial stimulation of cerebellum and primary motor cortex (M1) has been shown to enhance motor lear…
www.sciencedirect.com
The impact of realistic axonal shape on axon diameter estimation using… #DSFN5

The impact of realistic axonal shape on axon diameter estimation using diffusion MRI
To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereb…
www.sciencedirect.com
The relationship between methods of scoring the alternate uses task an… #DSFN5

The relationship between methods of scoring the alternate uses task and the neural correlates of divergent thinking: Evidence from voxel-based morphometry
Divergent thinking tests have been used extensively in neuroscientific studies of creativity. However, output from tests…
www.sciencedirect.com
Ott, C.V., Macoveanu, J., Bowie, C.R. et al. Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial. Neuropsychopharmacol. (2020). #DSFN5

Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial
Cognitive impairment is prevalent in bipolar disorder (BD) but treatments with pro-cognitive effects are lacking. Insigh…
doi.org
Takayanagi, Y., Ishizuka, K., Laursen, T.M. et al. From population to neuron: exploring common mediators for metabolic problems and mental illnesses. Mol Psychiatry (2020). #DSFN5

From population to neuron: exploring common mediators for metabolic problems and mental illnesses
Major mental illnesses such as schizophrenia (SZ) and bipolar disorder (BP) frequently accompany metabolic conditions, b…
doi.org
Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA‐intermediates and produce ATP under hypoglycemic conditions #DSFN5

Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCAâintermediates and produce ATP under hypoglycemic conditions
The aim of this study was to investigate endothelial glutamate dehydrogenase (GDH) expression and glutamate metabolism …
onlinelibrary.wiley.com
Genetic liability to major depression and risk of childhood asthma #DSFN5

Genetic liability to major depression and risk of childhood asthma
Major depression and asthma frequently co-occur, suggesting shared genetic vulnerability between these two disorders. We …
www.sciencedirect.com
Cerebellar – Premotor cortex interactions underlying visuomotor adapta… #DSFN5

Cerebellar â Premotor cortex interactions underlying visuomotor adaptation
Visuomotor adaptation (VMA) is a form of motor learning essential for performing day to day routines. Theoretical mo…
www.sciencedirect.com
Maturational trajectories of white matter microstructure underlying th… #DSFN5

Maturational trajectories of white matter microstructure underlying the right presupplementary motor area reflect individual improvements in motor response cancellation in children and adolescents
The ability to effectively suppress motor response tendencies is essential for focused and goal-directed behavior. Here,…
www.sciencedirect.com
Pollak, T.A., Kempton, M.J., Iyegbe, C. et al. Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis. Mol Psychiatry (2020). #DSFN5

Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis
Serum neuronal autoantibodies, such as those to the NMDA receptor (NMDAR), are detectable in a subgroup of patients …
doi.org
Influence of Processing Pipeline on Cortical Thickness Measurement #DSFN5

Influence of Processing Pipeline on Cortical Thickness Measurement
Abstract. In recent years, replicability of neuroscientific findings, specifically those concerning correlates of morpholog…
academic.oup.com
Schwann cell p75 neurotrophin receptor modulates small fiber degeneration in diabetic neuropathy #DSFN5

Schwann cell p75 neurotrophin receptor modulates small fiber degeneration in diabetic neuropathy
HFD induces obesity, mechanical allodynia and reduction of NCV in a similar fashion in WT and SC‐p75NTR‐KO mice …
onlinelibrary.wiley.com
Interleukin-8 dysregulation is implicated in brain dysmaturation follo… #DSFN5

Interleukin-8 dysregulation is implicated in brain dysmaturation following preterm birth
Preterm birth is associated with dysconnectivity of structural brain networks, impaired cognition and psychiatric disease….
www.sciencedirect.com
Only one week left to submit your brilliant abstract in order to present your research at the 5th HBP Student Conference in an oral and/or poster presentation! 👨🏾🎓👩🏻🎓
Take your chance:
https://www.humanbrainproject.eu/en/education/HBPSC2021/
#HBPSC2021 #studentsinHBP
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement #DSFN5

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement
The DNA repair protein Ercc1 is essential for microglia Microglia‐specific deletion of Ercc1 transiently induces an …
onlinelibrary.wiley.com
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