Hypersensitivity to Calcitonin Gene–Related Peptide in Post‐Traumatic Headache #DSFN5
Hypersensitivity to Calcitonin GeneâRelated Peptide in PostâTraumatic Headache
Objective To demonstrate that calcitonin geneârelated peptide (CGRP) induces headache exacerbation with migraineâlike features in patients w…
onlinelibrary.wiley.com
Molecular and cellular correlates of human nerve regeneration: ADCYAP1 /PACAP enhance nerve outgrowth #DSFN5
Molecular and cellular correlates of human nerve regeneration: ADCYAP1 /PACAP enhance nerve outgrowth
Carpal tunnel release provides an opportunity to study sensory nerve regeneration in humans. Schmid et al. show that cutaneous reinnervation correlate…
academic.oup.com
Increasing Muscle Speed Drives Changes in the Neuromuscular Transform of Motor Commands during Postnatal Development in Songbirds #DSFN5
Increasing Muscle Speed Drives Changes in the Neuromuscular Transform of Motor Commands during Postnatal Development in Songbirds
Progressive changes in vocal behavior over the course of vocal imitation leaning are often attributed exclusively to developing neural circuits, but t…
www.jneurosci.org
Cuellar-Partida, G., Tung, J.Y., Eriksson, N. et al. Genome-wide association study identifies 48 common genetic variants associated with handedness. Nat Hum Behav (2020). #DSFN5
Genome-wide association study identifies 48 common genetic variants associated with handedness
A genome-wide association study of 1.7 million individuals identified 41 genetic variants associated with left-handedness and 7 associated with ambide…
doi.org
NMDA receptor ion channel activation detected in vivo with [18F]GE-179 PET after electrical stimulation of rat hippocampus – Ali K Vibholm, Anne M Landau, Arne Møller, … , Jens CH Sørensen, David J Brooks, 2020 #DSFN5
NMDA receptor ion channel activation detected in vivo with [18F]GE-179 PET after electrical stimulation of rat hippocampus – Ali K Vibholm, Anne M Landau, Arne Mí¸ller, Jan Jacobsen, Kim Vang, Ole L Munk, Dariusz Orlowski, Jens CH Sí¸rensen, David J Brooks, 2020
The positron emission tomography (PET) tracer [18F]GE-179 binds to the phencyclidine (PCP) site in the open N-methyl-D-aspartate receptor ion channel …
journals.sagepub.com
Vasistha, N.A., Pardo-Navarro, M., Gasthaus, J. et al. Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner. Mol Psychiatry 25, 2313–2329 (2020). #DSFN5
Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner
Severe infections during pregnancy are one of the major risk factors for cognitive impairment in the offspring. It has been suggested that maternal i…
doi.org
Soler Artigas, M., Sánchez-Mora, C., Rovira, P. et al. Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality. Mol Psychiatry 25, 2493–2503 (2020). #DSFN5
Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality
Attention-deficit/hyperactivity disorder (ADHD) is a severely impairing neurodevelopmental disorder with a prevalence of 5% in children and adolescent…
doi.org
Erlangsen, A., Appadurai, V., Wang, Y. et al. Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study. Mol Psychiatry 25, 2410–2421 (2020). #DSFN5
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Family studies have shown an aggregation of suicidal behavior in families. Yet, molecular studies are needed to identify loci accounting for genetic h…
doi.org
TERT promoter mutations in primary and secondary WHO grade III meningioma #DSFN5
TERT promoter mutations in primary and secondary WHO grade III meningioma
We investigated the TERT promoter mutation (TERTpMut) in a population‐based, consecutive cohort of 40 malignant meningioma patients with tumor sampl…
onlinelibrary.wiley.com
Jarius, S., Pellkofer, H., Siebert, N. et al. Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients. J Neuroinflammation 17, 261 (2020). #DSFN5
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients
New-generation cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprote…
doi.org
Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome #DSFN5
Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by epigenetic silencing of FMR1 and loss of FMRP expression. Efforts to understand th…
www.biologicalpsychiatryjournal.com
Spinal manifestations of CLN1 disease start during the early postnatal period #DSFN5
Spinal manifestations of CLN1 disease start during the early postnatal period
The spinal cord appears especially vulnerable in CLN1 disease, a fatal inherited lysosomal storage disorder. Our data reveal a much earlier onset of s…
onlinelibrary.wiley.com
Yilmaz, Z., Halvorsen, M., Bryois, J. et al. Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder. Mol Psychiatry 25, 2036–2046 (2020). #DSFN5
Examination of the shared genetic basis of anorexia nervosa and obsess
Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
rdcu.be
Guidelines for TMS/tES Clinical Services and Research through the COVID-19 Pandemic https://psyarxiv.com/82bmu/ via @OSFramework #DSFN5
Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [18F]GE-179 PET #DSFN5
Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [18F]GE-179 PET
No PET radioligand has yet demonstrated the capacity to map glutamate N-methyl-d-aspartate receptor ion channel (NMDAR-IC) function. [18F]GE-179 binds…
www.brainstimjrnl.com
Yuste, R., Hawrylycz, M., Aalling, N. et al. A community-based transcriptomics classification and nomenclature of neocortical cell types. Nat Neurosci (2020). #DSFN5
A community-based transcriptomics classification and nomenclature of neocortical cell types
To understand the function of cortical circuits, it is necessary to catalog their cellular diversity. Past attempts to do so using anatomical, physiol…
doi.org
NeuroPycon: An open-source python toolbox for fast multi-modal and rep… #DSFN5
NeuroPycon: An open-source python toolbox for fast multi-modal and reproducible brain connectivity pipelines
Recent years have witnessed a massive push towards reproducible research in neuroscience. Unfortunately, this endeavor is often challenged by the larg…
www.sciencedirect.com
Complex IV subunit isoform COX6A2 protects fast‐spiking interneurons from oxidative stress and supports their function | The EMBO Journal #DSFN5
Highâfrequencyâfiring brain interneurons rely on cell typeâspecific energy metabolism to avoid oxidative stress.
www.embopress.org
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